How to you ameliorate the toxins inherent in shipping containers? Typically, those paints and pressure treated woods are not used indoors, and I would be worried about some of the chemicals? Second, in the climate here, how do you avoid mold? Metal is a prime target for condensation, and in the bay we are always around the dew point. If you insulate the walls, how do you avoid mold growth (maybe put insulation on the outside)? How about power/gas supply, HVAC, waste plumbing etc? How about moving it? Leveling it? it seems that they'll be substantially heavier than most mobile homes, so trailering with consumer vehicles will be hard, which makes them hard to deliver.
I've been in shipping container buildings before (e.g. Frietag store in Zurich) - they are not really a great size. Many Mobile homes that are comfortable feature pop-out sides. Any plans for expanding them?
Some real positives -
fireproof envelope,
Envelope can be welded to,
several formats available - including ones with side doors
can be "racked"
can be made airtight (allows you to specify air exchanges, rather than estimate them)
portability with the right equipment.