Yeah, I play chess sometimes, and I could not care less about how the board is oriented.
Most results that I found note that it probably does not affect the game that much. If you're planning to write down moves it may become confusing when someone with a correctly set up board tries to replay it.
If you set up the pieces the same way, you literally just play with different colors for the fields.
If you mirror your setup of pieces because you want the white queen to go to the white field, then you just play mirrored chess. Apply this transformation again to obtain the actual chess game.