For me it is possible that a big breakthrough would be changing our society in a close future, in even less than 200 years. I wouldn't know if 2 events may be happening, but at least one seems really probable. In ~20 years, we went from windows 95 to an overly connected world with small and powerful smartphones, the world is moving faster than ever.
CRISPR is an overview of what the revolution may look like. This technology may offers possibilities to hack DNA, this would be a huge revolution in term of health, but also totally change our world. Until now the medicine was trying to fix the body deficiencies by applying corrections afterwards. When we will reach DNA hacking capabilities, it would open the possibility to fix the real genetic cause of a disease even beforehand. It may be used to increase lifespan or boost human performance. Maybe it will be called the medical revolution?