With the pace of advancements in gene editing and the availability of biology maker-spaces, I expect that we're soon going to find out that the "3D printed guns" issue of hobbyist biology will be simple cells like yeast modified to synthesize illegal drugs. It may not be as efficient as industrial chemistry could be, but it only takes one entity producing such a cell before it will become a mainstay of illicit bathtubs everywhere. Every time I see an article like this I wonder why it hasn't already happened. We already have yeast that produce the active ingredients in cannabis, and I suspect the only reason nobody cares is because many people just grow plants anyway. How will this be handled once we can go a step further and make completely new genes that can make artificial drugs like LSD?