Jaron Lanier did experiments in VR with switched limbs, so your brain tries to make sense of a new "geometry".
I also felt regularly that all kinds of inputs are very stimulating for the brain and bolden the memory. For instance writing down with pen and paper requires more brain activity than a keyboard. Computers seem faster for note taking but the ease actually removes the colateral inputs that stimulate/challenge your brain and thus helps learning (you also have to reflect about what to trim and how to organize your notes, thus creating so semantic map of the topic).