Maybe it's just me, but I didn't find it all that difficult to get started with webpack after a few tutorials and samples. This seems like it hides away something that people should probably understand, which isn't all that difficult to get started with. Also when you start combining different packages in webpack (or encounter an error (or want to make some decisions in the config script)), the standard copy/paste boiler plate becomes less and less useful.
This looks neat, I just don't think it's likely to do away with configuration completely unless you've got a very standard setup.
That aside, it sort of sounds like the goal here is "a sort of package manager which also handles boilerplate"? Definitely sounds useful when you want to quickly try something new.