I used to ignore it, but I've decided since that while I'm not going to be remotely interested in the role they've proposed, I can at least clarify my background and career level should they have something more appropriate.
And for the total form email recruiter spam, I'll sometimes reply asking their rate range for W2 and 1099. I never get a response to those. Well, I'm lying, I did once and it was to say "let's discuss it on a call." No thanks, that means it's low. And being a small world up here, I knew who the client was anyway, and what they were trying to do. I had no business getting that email.