For example, in Chrome, add this as one of the Search Engines in the options dialog: http://www.google.com/search?q=%s&btnI=Im+Feeling+Lucky
I've associated that with the keyword "gg"
Now, when I go to the address bar and type a query whose first Google result I am confident will be the destination I want, I've got a great way to get there.
Example:
"gg imdb Forest Gump"
Will get me to IMDB's Forest Gump page. So you can pretty much imagine the power here, especially for reference sites. Type the site name and the query, and you'll end up where you want to be.
Most of those sites has an opensearch provider.
This has the same side effect for Google regarding ads as does the button. Although if a user wants to be taken directly to website ABC they prob aren't a good audience for ads.