The one thing I'd love to see, as a vim user and a scientist, is something like Matlab/RStudio/Spyder where you can explore variables that exist within a session. Maybe it could hook up to an ipython session and you could display it in a separate terminal and send commands with vim-slime to be updated in real time.
For the most part, when I need this, I revert to Rodeo (since it has vim bindings like RStudio's), but if I could ditch it that would be amazing. Nothing against Rodeo or other editors, but vim habits are hard to break.