Psychedelics are an investigators dream. They are safe in reasonable contexts and usage, while producing profound changes in consciousness that can be readily studied. All in the relatively well-understood context of neurotransmitters and receptor regulation.
Entire fields are based on chemicals that have specific physiological effects. When combined with genetic work, great progress can be made. And here we have a whole suite of compounds with both widely different and subtly different effects.
The prohibition of their use in research has hamstrung research in this area for decades.