https://noncombatant.org/2014/03/11/privacy-and-security-set...
There are also people who use Chromium, or particular configurations of Chromium, instead of Chrome. That's fine. But don't use forks of Chromium, no matter who maintains them, even if it looks like a sizable effort. You don't want your browser to be any number of days behind the Chromium patch cycle.
I use the browser integration for 1Password on OS X (I might not if I was on Windows). I'm generally not that worried about localhost privilege escalation. I am very worried about how well I can reason about cloud-based storage of any sort, and how it will interact with things like my browser.
KISS: keep your secrets out of cloud systems and your backups offline.
If you're very sophisticated, I like Tarsnap for online backups. But you have to be very sophisticated to use it.