I apologize for present anecdote when data is needed but I manage a Windows network with 100+ users and on a daily basis, Kaspersky catches 5-10 emails from Outlook that have nasty attachments. It prevents my users from opening these innocuous looking but nasty Invoice-Jan-2017.docx files. Without a good AV there is no way to know which Invoice-Jan-2017 has a virus/worm vs. which doesn't. Relying on the Office security feature is not sufficient because actual vendor/customers send macro-enabled files to us regularly.