I love Discord and use it on a daily basis, one of our main concern with my gaming group is the voice latency compared to TS, Mumble or Ventrilo but this is mainly due to the inability to host your own server.
One of the big missing feature we would like to have in Discord is the ability to assign special permission to our groups leader so they can communicate over voice chat to other other group leaders in other channels (global voice chat).
When we play PVP MMO's and have 40+ users all in the same channel calling shots its impossible to coordinate properly.
What we normally do is split the group in 4 so 10 players in 4 different channels and each group leaders are calling shots independently BUT can also communicate via voice chat to other group leaders. Basically there's a global voice chat for group leaders that no one else can hear but them.
Other than that Discord is amazing!