I have colleagues that prefer to drive that, and I only do it if it's the last option available. For me, the driving is my full day and them I'm exhausted while taking a flight I can nap or do work - much less unproductive time.
I think a 4-5 hour one-day drive is about my limit before I'll look hard at flight options. I also don't mind taking a flight for work on my "own time" since I find the whole process rather peaceful and can just zone out reading/catching up on news. Driving you'll have to pay me :)
To each their own though - I know without precheck and being able to jump the standby list flying would be much more miserable. It's certainly a race to the bottom that's sad to watch.