my $0.02 on this is you can work in SV for 6-12 mo, then if you play your cards right, you can transition into a remote role with your current employer. Myself and other friends have done this resulting in 6-fig salary anywhere we want to live.
If you got a job at a large tech company, I suspect many wouldn't be as flexible. If you want to work for a large tech company, I would find out if they have any current remote workers.