Just based on my own experience I never take fluoroquinolone antibiotics. I had one dose of Avelox and the next twelve hours were like a waking nightmare. They were twice a day pills, so I had to wait until that evening for the effect to pass. When I reported the reaction my physician told me to stop the drug immediately. She was quite vehement and sounded alarmed. The experience reminded me of the reaction I'd had to Cipro some years before, but worse. It was then that I looked them up and found they were in the same class.

Now I check. A few months ago I rejected a prescription of Levofloxacin from a new physician, and had him replace it with an antibiotic from a different class that I knew I tolerated well. My pharmacist agreed with my decision. She had taken Levofloxacin for a few days several years ago and it gave her permanent neuropathy in her hip and leg and balance problems. Actually, she said the neuropathy was permanent "so far." For all she knew it would go away, but after three years she wasn't expecting it.

Note that I'm reporting an n of 2 here. My brother says Cipro doesn't bother him at all. Do your research and make your own decisions.