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> This effect was shown mediated by heat shock proteins (hsps), which are very robustly increased in humans during sauna use.

Are they specifically heat related or any temperature stress might do?

I've been using cold water exclusively year round for last few years with occasional show/ice baths in winter time. I'm wondering if I'm missing something by avoiding warm water/saunas.

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Heat shock proteins are really a response to abnormal protein folding (generally speaking) and are found upregulated in a number of stress response scenarios; including cold, heat, and oxidative stress

Sounds like desert dwellers should live longer?

Re oxidative stress, can you give practical examples of how this is achieved for a person, what physical action creates it? https://en.m.wikipedia.org/wiki/Oxidative_stress suggests it's associated with lots of great harms - brain diseases, heart disease, etc.. How does that pair with longevity in practice?

>How does that pair with longevity in practice?

It doesn't. It pairs with shock proteins.

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