Yup, I run IoT Core in my Raspberry Pi 2, and run a C# UWP app on it to dynamically update my DNS settings. The UI is lovely, and the UWP API in general, too.

Both JIT and native modes of operation work. Hell, I can also build it for my desktop PC, and it's literally only changing the build target. It's phenomenally easy, so easy that I was actually a little in disbelief at first. .