In terms of ease of setup, I don't think any of these can beat Eero. And in spite of Netgear marketing dollars behind, Orbi, I hope EERO maintains the lead in this space, as they were the first one to push for mesh networking in consumer Wifi space.
It supports "extend your network" as hub spoke leaf model, with both wired-to-wireless bases (hubs) and wireless-to-wireless extenders / relays (spokes), and devices (leaves) will connect to strongest spokes or hubs as you roam.
You can have multiple wired-to-wired and wired-to-wireless bases on the same network each with its own wireless-to-wireless extenders or relays. This has worked and been solid (no reboots needed) for years.
Use the full size tower for hubs and airport expresses for spokes.