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Its more the difference between a cycle accurate system simulator and a functionally accurate system simulator.

Understanding the additional input from the mitochondria however might help with building more accurate FMRI type systems.

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That is a good distinction to make, but if we don't know exactly what the cycle is things get harder to figure out. Neurons hold state and we aren't sure how much yet, let alone a deterministic method of computing it. https://www.scientificamerican.com/article/new-estimate-boos...

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