You have to applaud Fuller for this insight which many similarly brilliant minds don't seem to grasp. Perhaps he can be included in this group;
1) Geodesic domes are a mathematically brilliant design but hopelessly impractical for many structures. Try fitting furniture in a curved house and dealing with a shape that either causes you to bump your head when you get to the edges or is so high in the center that you have an unnecessary volume to heat/cool.
2) The dymaxion car was similarly brilliant but completely missed the real reason that people buy cars: as a status symbol that looks cool, which the dymaxion did not.
The guy was a genius in my opinion but the failure of his incredible ideas to take off on a large scale shows that perhaps they appeal to my mind more for their idealism than practicality.
NOTE: Am currently reading Operating Manual For Spaceship Earth