Edit (on second thought): They are probably using canvas and not other trickery, then yeah, current versions of IE are pretty screwed.

Original post:

Since I am not involved in the project, I can't know for sure. But it is presented at a jQuery conference and, really, the main reason why anyone would use jQuery (or any similar intermediate layer written in JavaScript) is to get around cross-platform issues easily. That said, I'm pretty sure that at this stage it probably does not work in IE but I did not see any functionality in the video that suggests that it would not work in IE with a bit of effort put into it before launch.

It probably performs like a dog, though. :-)

On the flipside (and another cool project): FreeCiv (http://www.freeciv.net/) did not seem to be bothered with getting native IE functionality in place (it requires Chrome Frame).