Even with a 256GB drive and a number of tweaks like hosting the Windows pagefile and temp from a passthrough disk, disabling Windows automatic updates, and using an immutable disk containing the OS install/multi-attach for copy-on-write behavior, VBox still used a ton of space to track the differences from my baseline snapshots. Even starting the VM quickly consumed 10-20GB in the new disk image. Was hard to conclude anything other than it wasn't a viable "dual workstation" setup and I capitulated and moved to Windows 10.
Sucks, because it was really quite nice to have a unix under the hood, though WSL makes this a bit more tolerable in Win 10 AU.