Maybe, but not on purpose. Nasa goes to great lengths to sterilize probes going to Mars. http://mars.nasa.gov/mer/technology/is_planetary_protection....
That's a big hurdle to colonization and commercial exploitation. Because it means you have to show you're not contaminating alien life.
I would be really excited if we find traces of life on Mars but, at the same time, it would probably delay commercial exploitation and colonization for decades...
Obviously you cannot sterilize astronauts. But they could be restrained to landings outside of the special regions, which are the most promising for astrobiology.