I've been in biomedical research for 15 years, and I am leaving the lab atm. Many of my peers are as well. It's not a viable or enjoyable career anymore. Funding is extremely political, and proposal reviews border on arbitrary. Typically, the funding has been decided by seniority and politics, and the review is justification.

I imagine that it will get better eventually, but I can't wait for that to come to pass, and I can't in good conscience advise others to do so.