At the risk of stating the obvious, if you're commuting back and forth between SFO and PDX to launch a business you are not the "little guy".
The "little guy" earns minimum wage and can barely afford to keep their own apartment, let alone rent out a spare one when they're travelling regularly between two cities. All AirBnB does is raise the "little guy"'s rent when the other apartments in their building become short-term hotels for tourists.