There's actually work being done to build PHP frameworks that get around this with ReactPHP, ZeroMQ, Photon, etc. Essentially this is what HHVM does as well, by at least keeping your compiled bytecodes in memory (similar to APC/eAccelarator/ZendOptimizer, etc).
See: http://reactphp.org http://www.photon-project.com https://gnugat.github.io/2016/04/13/super-speed-sf-react-php...
Even the idea of an alternative runtime for PHP (ala HHVM) is nothing new: http://quercus.caucho.com