"Furthermore, we found strong similarities in what may be called the 'gut profiles' of the Crohn's-affected families, which were strikingly different from the Crohn's-free families."

It seems that fecal transplant (or pills based on them) can alter/fix gut profiles[1]. I wonder if someone tried fecal transplant to cure Cron's disease.

[1] https://youtu.be/e_dF1N-Ckbw?t=1m44s

Edit: It seems this has been tried and pretty successful[2].

"A recent publication in the journal Inflammatory Bowel Diseases titled, “Fecal Microbial Transplant Effect on Clinical Outcomes and Fecal Microbiome in Active Crohn’s Disease,” reports seven of nine patients with Crohn’s disease were effectively treated using FMT in a Seattle Children’s research study."

[2] http://pulse.seattlechildrens.org/study-suggests-fecal-trans...