http://donhopkins.com/mediawiki/index.php/AQuery
Morgan Dixon did some wonderful work at the University of Washington called Prefab. Some of the links from my page to his papers are broken, but here's his web site and a demo:
Prefab: The Pixel-Based Reverse Engineering Toolkit Prefab is a system for reverse engineering the interface structure of graphical interfaces from their pixels. In other words, Prefab looks at the pixels of an existing interface and returns a tree structure, like a web-page's Document Object Model, that you can then use to modify the original interface in some way. Prefab works from example images of widgets; it decomposes those widgets into small parts, and exactly matches those parts in screenshots of an interface. Prefab does this many times per second to help you modify interfaces in real time. Imagine if you could modify any graphical interface? With Prefab, you can explore this question!
https://www.youtube.com/watch?v=w4S5ZtnaUKE
Imagine if every interface was open source. Any of us could modify the software we use every day. Unfortunately, we don't have the source.
Prefab realizes this vision using only the pixels of everyday interfaces. This video shows how we advanced the capabilities of Prefab to understand interface content and hierarchy. We use Prefab to add new functionality to Microsoft Word, Skype, and Google Chrome. These demonstrations show how Prefab can be used to translate the language of interfaces, add tutorials to interfaces, and add or remove content from interfaces solely from their pixels. Prefab represents a new approach to deploying HCI research in everyday software, and is also the first step toward a future where anybody can modify any interface.