On the other hand, when using Asm you can often leverage techniques not possible in HLLs to avoid complexity and abstraction. This is a fact which seems not commonly known, even in CS courses involving Asm, as those tend to be more about inspecting compiler output and the few "write in Asm" exercises are mimicing code that a compiler would generate, which IMHO misses the whole point of writing in Asm.
Here is an operating system containing many nontrivial applications, all written in 100% Asm:
Among other things, it contains a minimal yet functional web browser (around the same level of minimalism as Dillo or NetSurf, i.e. no JS or fancy CSS), and the whole package fits on a single floppy disk.
An entire OS with kernel, drivers, and applications in total can be smaller than a "Hello World" application in a "modern" programming language (which depends on countless other external libraries too, including an OS several GB or more.) It really makes you think.