I've gotten more than a hundred rejections in a year (140+), and i gotta say, it was terrible.

Having said that, i think this is generally good advice.

Looking back, there are a lot of similarities to the common "failed startup" experience. I worked on the novel for five years (got plenty of feedback along the way) but getting it picked up (traction?) was a bust.

And it wasn't "safe to fail" as someone mentioned up above. It hurt, emotionally, physically (90 hr weeks).

Lesson learned. I try to be comfortable with failure now, it's not a friend or anything, but it'll stop by, a lot.