It was one of the larger economies; as it will now be an isolated island with no automatic access to the European market, it's value will be lost to a lot of businesses.
What I'm arguing is that the UK has plenty of bargaining chips, and can trade elsewhere if it doesn't feel like it's getting a fair deal in the EU.
Now it will be negotiating with a block of them. The UK just willingly decreased their leverage so they had free will.
Thank you, from all of America. You managed to be completely embarrasing in your 2016 election cycle, before we are really able to be shockingly shameful in front of you.
Brits are polite to the end.