I felt this way because that's exactly where I'm in now and I don't seem to find a way out. Need some advice here.
Seriously though, it sucks that you're going through a rough time. I don't think there's a magic bullet - you just have to keep on moving and see where life takes you. If you end up having to move back to your home country, will that really be the worst thing imaginable?
Even if your standard of living takes a hit, your family will survive and you'll be together. I've been down a similar road before, and although it seems calamitous at the time, eventually you adapt and it's just life.
I don't know that I can give you a lot of advice, since your life is bound to be so much different than mine, but I can tell you what we did.
I own a small business (14 employees, <1MM in revenue) that does essentially technology-oriented bookkeeping. I'd say we're a startup, except that we're bootstrapped and capital comes from customers, not from VCs--not sure if that excludes us or not. A couple of years ago, my wife and I decided to move with our 4 children to Sweden for a year, where she has two sisters. We wanted our children to be able to speak Swedish, not just English, and I wanted to see the world a bit more. (I actually commented on a hacker news piece while there: https://news.ycombinator.com/item?id=8731296)
Things got a little crazy when we found out before we moved that she was pregnant with number 5--and that if we moved he was going to be born in Sweden. We had only 10,000$ saved up, but we decided to take the plunge knowing that I could work remotely on my business here and I had 60k income. Note that her being a dual citizen was critical--we knew she would be able to take advantage of the free health care.
It was an awesome year, with some powerful struggles--living above the Artic circle in a foreign country made me look at things in a whole new way.
The three things that made it possible were 1) We had a support group (her sisters) in Sweden willing and able to help us 2) I had a remote job and 3) she was a citizen.
We came home broke, and I lost a few customers by not being able to focus as easily, but I have no regrets. My company didn't go bankrupt, both me and my children now speak fluent Swedish, and we have an amazing circle of close friends that we would otherwise never have gotten to know.
I can't say it's easy, but the moment my wife & I decided _as a team_ to do it, I knew it was possible.
Having kids just means that, at worst, you have to wait until they're 18 before you run off globetrotting. In the meantime you can still see the world, but you might be limited to their holiday periods.
If you're on a H-1B then don't forget you've seen more of the world than the majority of people who don't leave their own countries, ever.
Aging parents are trickier, but this comes down to how much money you have and how important it is that you are the primary carer. It sounds cold to put it in those terms, but if it comes down to it, that's the decision you're making - 24/7 care is certainly something you can buy (and might actually be better than what you personally are be able to provide).
Moral of the story - if its bad for you, its always worse for someone else. Not something that may make you feel better, but its important to try not to lose some perspective.
You mean you have a trust fund and all? Ask your advisor then.