> No. Dijkstra's algorithm operates on fundamentally discrete structures (finite graphs), whereas the simplex method solves linear programming problems with continuous variables (conceptually ranging over the reals, although of course on a computer one uses floating-points or some other approximate representation).
I think you've misunderestood the grandparent. Try to think of the vertices of the simplex as vertices in a graph, and edges on the simplex as edges on the graph. The (primal) simplex method chooses an entering variable by saying, "which edge from this vertex improves the objective most quickly?"
The reason the graph search doesn't turn into Dijkstra's algorithm is that we would never have any reason to backtrack. The next basis is always at least as good as the last, so we don't "get stuck" and we don't ask whether we would rather have gone another way earlier on.
EDIT:
> To see why interior point methods are more efficient...
I know they exist, but I've never seen a problem for which interior point methods are actually faster in practice. My experience isn't too deep with very large LPs, mind -- mine tend to have tens or hundreds of thousands of variables, not millions.