You obviously didn't read my post before listing your pet list of things that are irrelevant. Macros are bad. They are only a benefit to those that are delusional enough to think they are a rockstar.
> Ability to do systems programming without having to use an external language?
I have no idea what this even means today. "systems programming". Are you from 1980? Perl is vastly more connected to *ix than any Lisp ever developed. There is nothing you can't do in Perl. Ruby and Python aren't that far behind, either.
> AOT compilers to native code
Totally unnecessary. I can't even think of a reason you'd want this in 2016. Maybe in 1989. But anyway, "native" is disingenuous when talking about Lisp. Unless you just like being an asshole. Lisp requires a GC, and due to the dynamic nature you're constantly jumping through dynamic/static hoops to get exactly what you want. The resulting executable is massive. Perl and I think Python can also compile to "native code".
> REPL environments with GUI debuggers, with fix-and-continue?
Uhm. Yes? The REPL GUI debugger everyone uses today is called Chrome. You seem to be stuck in the stone age. Web and mobile development are where it's at.