I get RSI in my wrists/hands from typing/coding. But three small changes to my desk set up keep it almost entirely at bay:

1 - Use a vertical mouse. I like Evoluent best but they are expensive. Anker is much cheaper but not quite vertical enough for my liking.

2 - Set up my keyboard so that it tilts -away- from me. Meaning the back (F-key side) is about 1-2cm lower than the front (space bar side).

3 - Type with my wrists/palms raised up a bit and -not- resting on the desk or keyboard.

All of these things help keep my wrists and hands in a straight line with my forearms which seems to be the key for me.

It doesn't hurt to occasionally do some wrist stretches too.