I wonder if there's any demand for a pre-built whitelist for NoScript that includes stuff like Amazon, Google, Apple, banks, and most other popular sites. The admin would err on the side of allowing scripts to run, while the default-block rule would still block unknown and ad/tracker domains. It would obviously be less secure than an intelligent user making all their own decisions, but it would make the barrier to using NoScript much lower.
Edit: While I'm musing on this, I wonder if NoScript could use a UI overhaul. A little icon that says "Something broken? Try activating these domains" with some heuristics e.g. first try allowing the current domain, then stuff on common CDNs, then maybe digging into DNS records or SSL certs for common ownership...