People are already different in terms of capabilities. Yet they are equals in terms of rights, and there is no reason that should change, even with this kind of things.
And nothing will stop them from pursuing political and business careers at equal terms with the rest of us. Of course, their superior genes will let them get ahead, but regardless, that's what already is happening - more genetically smart and charismatic people can get into positions of power easier than others, and we seem to be quite OK with it.
I personally believe that smart people don't feel any need to get privileges of any kind, since they are by definition more capable to attain their goals anyway. You may not give a dog lots of rights, but you don't see it as a threat or a competitor either.
I shudder to think how a greatly magnified version of that will turn out.