Most of the problems described in the articles can be solved by simply using promises. Error handling is centralized in your chain and any function can throw and just like Python or Ruby you can catch anywhere you want. As for consistency between callbacks, promises and generators, just pick one. We switched from callbacks to promises and it was a great move. Error handling greatly improved and the code looks a lot nicer. No more callbacks hell. Ever.

We switched our backend from Python to Node almost 2 years ago now and it was a great decision for us. If you handle a code base that deals with a lot of async requests Node is definitely a top contender.