For anyone using TypeScript to build your Node.js code, you can now switch your target to es6/es2015 in your tsconfig.json:

    {
        "compilerOptions": {
            "target": "es2015",
            "module": "commonjs"
        }
    }

Assuming you're not using that 7% (http://node.green/) :)

Just make sure to update your package.json to take a hard dependency on Node 6+ if you do that:

    { "engines" : { "node" : ">=6.0.0" } }

This will make it so that ES6-compat is assumed and TS won't transpile ES6 functionality, but it will use commonjs for modules, which means your TS will almost be a 1:1 mapping with the compiled JS and everything should just work.