The animation definitely seems the most difficult (and subjective), but also the most cool! Body hacking via computed geometry!
Invisalign (align technology) uses almost the same workflow. Market cap $5.89B.
If you could move the workflow over to something based on WebGL / three.js - you could make this accessible to dentists in developing countries. Could be an awesome open source project.
I think "allowing" it to be used in the US would open yourself up to too much liability though :(