I like the idea of React. I like it even more when you take out all the frills and boilerplate. If you haven't already, I would encourage you to give Clojurescript and Reagent a try:

https://reagent-project.github.io

I decided to use it for a small client for a chat server my company runs. The initial environment setup on OS X wasn't the smoothest, but once I got that taken care of the actual development was very pleasing and quick. You need to know just a few core concepts and then you can more or less replicate the common patterns you use in React - application state, component properties, local component state, initial values for local state, etc.

Along with that, you get immutable data structures and the benefits of the Google Closure Compiler out of the box. Give it a shot!