I think the worst thing I saw ever was this woman who was having cereal while going 75+ MPH on the highway. She was holding the bowl in her left hand, she'd move her right hand off the wheel, reach down (assuming to the cup holder), grab a spoon, lift it, dip in the bowl, move to her mouth and then return the spoon back to its position before reaching up to grab the wheel again. The whole procedure takes somewhere north of 5 seconds to accomplish. Add to that the fact that she was going at least 20 over the limit and that at any point in time, her eyes are shifting to look into the bowl to see if she's scooped enough, down to the cup holder to check and make sure she's picked up/dropped the spoon properly and you're in trouble.
It has to do with orexin. Orexin helps keep you awake. But you produce less of it when you are sedentary or bored. When there is mental engagement with a task, it is easier to stay awake.
The very qualities that make limited access highways useful for most of us, to get places more quickly, make them deadly for people with orexin-deficiency sleep disorders.
That's why I hope polyphasic sleep experimenters only drive on the interesting or challenging stretches of road.