I think it's hard to say without knowing more. On the one hand, paying in btc probably restricts the number of people willing to use your product by virtue of there being not that many people who have btc accounts. On the other hand, it might make you more popular with a small group of people.
Most great products start with a core of really happy users, and then expand over time. Do you have users that love you and use your product every day? Many times a day?