The fact is that audio latency, hardware support and plugin support (amongst many other factors) are always likely to be severely limited when running in a browser environment of any kind, let alone on top of the Flash run-time.
This is a great toy, and huge respects to the creator, but if you're even remotely serious about making music, you'll be ditching this within minutes and picking up a custom-built music environment which goes nowhere near a web browser at all.
Sorry, but anybody implying that this is a good reason to retain Flash is going to have to come up with a much more convincing argument.