It is very important to distinguish between fructose and glucose sugars. Fructose is actually much more poisonous then glucose is. It seems metabolized mostly like alcohol.
Now, with the high fructose corn syrup everywhere, makes the situation not better.
https://www.youtube.com/watch?v=dBnniua6-oM
EDIT: fructose is not so problematic if it's still embedded in fibers like in fruit. Bacteria then eat most of it, before it is absorbed.