It's pretty difficult to take anything on that list seriously if they're going to blatantly misrepresent statistics like that.
This Breuckmann study repeatedly found about a 2.5 to 1 increased incidence of heart attack from marathon running over sedentarism. The number of marathons run was an independent and significant predictor of the likelihood of myocardial damage.
http://www.paleonu.com/panu-weblog/2009/11/1/cardio-causes-h...
The 2.5 to 1 increased incidence of heart attack from marathon running over sedentarism bit is BS, and flatly contradicted by studies already linked to on this thread.
It doesn't seem crazy to think that there's such a thing as too much exercise, but there are a couple problems with this top ten list you cite.
First, maybe there are right and wrong ways to run a marathon and the people doing it the wrong way have skewed the results of these studies.
Second, if running a marathon is bad, then surely running half a marathon is still not good, right? What about a quarter-marathon? One mile? Etc. I think everyone agrees that there is some amount of running that does more good than harm. But it's not that helpful to simply say that marathons cause harm without looking at the good (if any) they do and then trying to find the distance that properly balances good and harm.
(Having said that, I don't see the point in twisting statistics to lambast marathons either. I plan to run my first one next year regardless!)
Lots of people kill themselves with marathons. Maybe there's a right way to do it, but obviously it's easy to do it the wrong way. Which makes marathons dangerous until someone figures out your right way.
"if running a marathon is bad, then surely running half a marathon is still not good, right?"
No. Does not follow. As you say, there are probably distances where the good far outweighs the bad. 26 miles is not that distance.
Distance running is what humans evolved to do, according to a good deal of evidence. Admittedly, running on asphalt and concrete with awful form created by a lifetime walking and running in awkwardly built shoes and sitting in chairs all day is not what humans evolved to do.
See http://en.wikipedia.org/wiki/Pheidippides for details.
So, after running 75 miles a day for the first two days, don't run another 25 miles the next day.
PS: The story is improbable, as the Athenians would more likely have sent the messenger on horseback.
While some of that list is anecdotal, most is based on relevant studies, and on DeVany's long interest and observation of patterns of health (as an athlete and economist). His perspective is a necessary antidote to the popular conception that ever-longer distance-running delivers a monotonically-increasing level of healthiness.
DeVany suggests -- with evidence -- that instead, the optimal activity involves bursty, varied, intense exertion more than marathon-like exertion. The stresses and rhythmic pace of marathoning damage some systems more than they help.