While some of the data is surprising (22x average slowdown for TypeScript dropping to 6.5% overhead when fully typed) the paper ignores the reason why people kicked and screamed for the functionality to begin with. It had nothing to do with run-time performance.
Obviously the tools will improve and you can always strip out the annotations if performance is an issue.
Reticulated Python is still an order of magnitude faster than Ruby, so obviously performance doesn't render a technology "dead."