Lets see what happens to react. I hear React is building in support for Relay, React Native, other facebook stuff. I <3 <3 <3 react, they have done an amazing job so far, as a React.js consultant and early adopter I owe my financial well-being to React, but big projects from big companies have weird incentives, Conway law, everything made by big companies inevitably goes to shit, yada yada. Maybe Relay ends up being not the best solution to the client/server query composition problem (IMO its not). Maybe people will get burned by 50-shades-of-flux (IMO the Great Flux Wars have barely started) and for the type of company that writes a ton of javascript, the framework pattern will come in vogue again (IMO). Maybe there will be an explosive patent lawsuit where Facebook decides to weaponize its "defensive" patents for whatever reason. I personally believe all of the things in this paragraph will happen in the near term.

Edit; Sorry i meant Conway's Law https://en.wikipedia.org/wiki/Conway%27s_law