Wikipedia claims the fastest typist in the world uses a Dvorak. http://en.wikipedia.org/wiki/Dvorak_Simplified_Keyboard so you draw your own conclusions about speed from this
I am sticking to the Dvorak because I don't feel as much strain on my wrist as compared to using a QWERTY. I have had a pain in my right wrist which hasn't occurred since I started the Dvorak. (Note: It could also be due to the slowdown in speed during the transition process).If I get an increase in speed it is a bonus.
A small bonus on using the Dvorak is that I don't need to bother about people looking at my keyboard when I am typing my password.
Cons: 1) Pair programming is a pain if the other guy doesn't use Dvorak. Having to switch keyboard layouts often isn't fun, unless of course your workplace allows you to install DVAssist 2) When using outside terminals, such as Internet cafe, it is highly unlikely you are going to be able to switch keyboard layout. 3) On a Mac, the shortcuts still follow the QWERTY keyboard, so the Apple-C key is really an Apple J key.
Signed A QWERTY keyboard typist for 25 years